HMS Defiant

From Memory Alpha, the free Star Trek reference.

The HMS Defiant was a British warship from the 18th century.

The USS Defiant (NCC-1764) was named after this ship, and had a painting of it in its Briefing room. (ENT: "In a Mirror, Darkly, Part II")

The USS Defiant (NX-74205) was another namesake in the 24th century. (DS9: "Defiant")

Background

While there has been a long line of British naval vessels to bear the name Defiance, including a torpedo school ship and three United States naval vessels, there never was an HMS Defiant serving in the Royal Navy in real life. A fictional Defiant was seen in the 1962 movie Damn The Defiant! (based on the Frank Tilsey novel Mutiny), which may have been the namesake for the Constitution-class starship.