Lady with an Ermine
From Memory Alpha, the free Star Trek reference.
The Lady with an Ermine is a painting done by the Human Leonardo da Vinci in the late 15th century in Europe on Earth. The painting depicted a human female holding an ermine, a small mammal.
The painting was also found among the relics in Kathryn Janeway's da Vinci holodeck program. (VOY: "Scorpion", "Concerning Flight")

