Terrellian plague

From Memory Alpha, the free Star Trek reference.

You might also be looking for the Tarellian plague.

The Terrellian plague is a devastating viral infection, renowned for the excruciating discomfort its victims suffer.

The first symptoms of Terrellian plague is a minor headache, only shortly later do the symptoms become much, much worse. (ENT: "Singularity")

It is often used in hyperbole or as an exaggerating comparative: "It's heartburn, Neelix, not the Terrellian plague." (VOY: "Message in a Bottle")