USS Shepard

From Memory Alpha, the free Star Trek reference

The USS Shepard was a Federation starship in service during the later 23rd century, under the command of Captain Clampett. The Shepard's communications officer was Trillya.

The Shepard was among the vessels disabled by the Whale Probe approaching Earth in 2286.

In the distress call relayed to Starfleet Command from Trillya, it was noted that the ship had lost all power and that the captain had quarantined all but minimal support crew due to failure of bio-sterilization capsules containing the Vegan D virus, which was believed to have infected the entire crew and was responsible for the deaths of fifteen crew members. Trillya further noted that the Shepards atmospheric regeneration and reclamation systems were nonfunctional, and all medical supplies were spoiling due to the shutdown of refrigeration aboard the ship. She warned that life support systems would be exhausted within eight hours, and requested further advice from Starfleet in resolving their situation. (Star Trek IV: The Voyage Home)

The Shepard was named after Alan Shepard, the first American in space.